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During IVF treatment

1. PGS: Pre-implantation Genetic Screening 

One of the most common causes of unsuccessful pregnancy is chromosomal abnormality (known as ‘aneuploidy’), which means there is a loss or gain of one or more chromosome. Pre-implantation Genetic Screening (PGS) using Next Generation Sequencing (NGS) involves screening embryos for chromosomal defects during a standard IVF cycle, in a process called EmbryoSelect.

Embryos with the correct number of chromosomes can then be selected for transfer which improve the chances of pregnancy and the development of a healthy baby.

The benefits of PGS are:
  • Reduces the likelihood of miscarriage
  • Reduces overall cost associated with multiple IVF cycles and embryos
  • Faster time to pregnancy
PGS may be appropriate for couples with:
  • Maternal age 36 years and over 
  • Repeated IVF failure 
  • Recurrent miscarriage 
  • A previous pregnancy with a chromosome abnormality
PGS can be carried out in a standard IVF cycle and includes an embryo biopsy and genetic testing.  Each client has a personalised plan, your fertility doctor will be able to advise the cost to include PGS with your treatment and tell you more about the process. 

2. PGD: Pre-Implementation Genetic Diagnosis

If you or your partner have a family history of genetic disease or you are a known carrier of a genetic condition, you may also wish to include preimplantation genetic diagnosis (PGD) as part of your IVF treatment.

Preimplantation genetic diagnosis (PGD) is a procedure used to test an IVF embryo for a specific genetic condition (such as cystic fibrosis or Huntington disease). This can prevent certain diseases being passed on to a child.

PGD differs from Pre-implantation Genetic Screening (PGS) in that it tests for one specific known genetic condition. PGS screens the embryo for chromosomal defects. PGD can be offered in combination with PGS where a disease-free and chromosomally balanced embryo can be selected for transfer.

Your fertility doctor will be able to discuss the associated costs in your personalised fertility treatment plan. Clients who are identified as a high risk carrier may have access to public funded IVF treatment.